DBT-MRC funded Centre Partnership between the National Institute for Research in Tuberculosis, Chennai and the University of Cambridge
The DBT-MRC funded Centre Partnership between the National Institute for Research in Tuberculosis, Chennai and the University of Cambridge builds on an existing programme of collaborative research on MDR- and XDR- TB using clinical and modelling (zebrafish models etc.).
Understanding Antimicrobial Resistance Mutations in Tuberculosis: Towards Personalised Treatment to Combat Multi-drug Resistance
TB is recognised as one of Brazil's leading infectious diseases, with over 70,000 cases notified each year. There has been a significant increase in the number of diagnosed MDR-TB cases, with 10% of those also resistant to the two most important second-line class drugs (XDR-TB). In line with WHO Stop TB Strategy, this project will focus on emerging sequence-based diagnostics to improve accuracy of individual patient treatment.