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Ulrich scan of a virus Rotavirus gastroenteritis in a major cause of morbidity worldwide and of mortality in low and middle income countries. Considering that rotavirus disease is either transmitted by direct contact or water borne, good domestic and personal hygiene is the standard approach for disrupting the faecal-oral transmission route of this pathogen. Treatment is usually by oral re-hydration.

Recent introduction of rotavirus vaccination and their universal application have significantly decreased  the number of cases of rotavirus associated diarrhea and also mortality. However, the vaccines are proving less effective in tropical areas.

Dr Ulrich Desselberger of the Department of Medicine at the University of Cambridge has published a comprehensive review on rotaviruses in 2014. For more details see the link below.

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The Cambridge Centre for Global Health Research is funded by the Wellcome Trust. In close collaboration with The Wellcome Trust Sanger Institute, it supports researchers working in public health and tropical medicine to develop their careers, and foster interchange between institutions in the UK and those based in low- and middle-income countries.

Image: Desselbergeret al;

British Medical Bulletin 2009;90;37-51